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  • Writer's pictureElena Cora

Optimizing Male Fertility: Medicines for Increasing Sperm Count and Motility

Low sperm counts and motilities have long been linked to infertility. Though there are medications designed to increase both numbers, more research needs to be conducted before we know whether these remedies actually help people become pregnant.


Many medications have an immediate and direct effect on sperm count and motility; others can have indirect impacts; for example, ACE-inhibitors such as captopril may decrease semen parameters but this effect is reversible with reduced medication dosage.




Clomiphene citrate:


Clomiphene citrate is a selective estrogen receptor modulator (SERM), widely used to stimulate gametogenesis in men with lower sperm counts. This drug works by blocking xenoestrogens' action while stimulating Leydig cells' production of testosterone and improving motility - this medication can be taken orally via tablets.


Doctors may prescribe Clomiphene Citrate to male patients who are experiencing unexplained infertility, and it has proven itself effective when other options have proven inadequate or unavailable. Clomiphene citrate may treat oligoasthenospermia or hypogonadism while increasing pregnancy chances.


Clomiphene can induce ovulation in patients suffering from an ovulatory or oligo-ovulatory infertility and increase sperm counts in semen, and should be prescribed for up to six months. Due to clomiphene's increased risk of multiple pregnancy, patients should use ovulation predictor kits only after treatment has ended and avoid testing for LH surges that occur shortly before starting on Clomiphene cycles.


Hormones:


Hormones are chemical substances secreted from endocrine glands (the glands responsible for producing hormones). Hormones play an integral part of many important body functions; for instance, they help produce sexual hormones (estrogen for women and testosterone for men) to regulate menstruation cycles and pregnancy as well as produce sperm in testicles which are organs located beneath your penis in your scrotum.


Clomiphene citrate works by stimulating your hypothalamus and pituitary gland to produce more follicle stimulating hormone and luteinizing hormone, both of which increase sperm production in your testes. Our doctors can prescribe various medications to boost testosterone levels such as human chorionic gonadotropin (HCG) injections under the skin as needed, in addition to monitoring testosterone levels and adjusting your medication dosage as Akseer e kiram.


Antibiotics:


Antibiotics may have an adverse impact on fertility. This is particularly true of antibiotics that target DNA of sperm. Some antibiotics, like tetracycline, can reduce both count and motility of male sperm in men; before taking any antibiotics it is wise to consult your physician, especially if trying to get pregnant.

 

Antibiotics may negatively impact sperm health by upsetting the balance of good bacteria in the body - essential for healthy digestion but often decimated by antibiotics. Thankfully, supplements exist which can restore that balance and thus improve sperm health.


Antibiotics can induce oxidative stress in sperm, leading to decreased motility. Their impact can be mitigated with antioxidants such as SODs (superoxide dismutase). These readily available and inexpensive molecules have been shown to significantly increase motility among men with low counts or motility levels. One study even demonstrated this with oral supplementation of SODs increasing motility rates by an impressive 305%!


Gene therapy:


Gene therapy is an exciting new field that holds great promise in rapidly treating genetic diseases and disorders. This therapy involves inserting genetic material directly into cells to treat disease or enhance fertility; its advantages include lower costs and reduced toxicity; however, there may also be unique ethical considerations surrounding its implementation.


Before beginning any hormonal testing or treatment, make sure to carefully note your key symptoms and family history in order to help your physician better comprehend your condition. Hormonal tests measure levels of testosterone and follicle-stimulating laboob e kabeer ajmali.


Numerous supplements may help combat low sperm count and motility issues, including those containing the herb fenugreek which has been shown to improve testosterone levels and quality, vitamin E and C can both boost production of sperm cells; one study demonstrated this increased both counts and motility among men suffering from oligospermia.

 

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